Genetic determinants of co-accessible chromatin regions in activated T cells across humans

Genetic determinants of co-accessible chromatin regions in activated T cells across humans

Rachel E Gate, Christine S Cheng, Aviva P Aiden, Atsede Siba, Marcin Tabaka, Dmytro Lituiev, Ido Machol, M Grace Gordon, Meena Subramaniam, Muhammad Shamim, Kendrick L Hougen, Ivo Wortman, Su-Chen Huang, Neva C Durand, Ting Feng, Philip L De Jager, Howard Y Chang, Erez Lieberman Aiden, Christophe Benoist, Michael A Beer, Chun Jimmie Ye, Aviv Regev

Nature Genetics 2018

Multiplexed droplet single-cell RNA-sequencing using natural genetic variation

Multiplexed droplet single-cell RNA-sequencing using natural genetic variation

Hyun Min Kang*, Meena Subramaniam*, Sasha Targ*, Michelle Nguyen, Lenka Maliskova, Elizabeth McCarthy, Eunice Wan, Simon Wong, Lauren Byrnes, Cristina M Lanata, Rachel E Gate, Sara Mostafavi, Alexander Marson, Noah Zaitlen, Lindsey A Criswell, Chun Jimmie Ye

Nature Biotechnology 2017

Discovery of stimulation-responsive immune enhancers with CRISPR activation

Discovery of stimulation-responsive immune enhancers with CRISPR activation

Dimitre R. Simeonov, Benjamin G. Gowen, Mandy Boontanrart, Theodore L. Roth, John D. Gagnon, Maxwell R. Mumbach, Ansuman T. Satpathy, Youjin Lee, Nicolas L. Bray, Alice Y. Chan, Dmytro S. Lituiev, Michelle L. Nguyen, Rachel E. Gate, Meena Subramaniam, Zhongmei Li, Jonathan M. Woo, Therese Mitros, Graham J. Ray, Gemma L. Curie, Nicki Naddaf, Julia S. Chu, Hong Ma, Eric Boyer, Frederic Van Gool, Hailiang Huang, Ruize Liu, Victoria R. Tobin, Kathrin Schumann, Mark J. Daly, Kyle K. Farh, K. Mark Ansel, Chun Jimmie Ye, William J. Greenleaf, Mark S. Anderson, Jeffrey A. Bluestone, Howard Y. Chang, Jacob E. Corn, Alexander Marson

Nature 2017

Parsing the interferon transcriptional network and its disease associations

Parsing the interferon transcriptional network and its disease associations

Sara Mostafavi, Hideyuki Yoshida, Devapregasan Moodley, Hugo LeBoité, Katherine Rothamel, Towfique Raj, Chun Jimmie Ye, Nicolas Chevrier, Shen-Ying Zhang, Ting Feng, Mark Lee, Jean-Laurent Casanova, James D Clark, Martin Hegen, Jean-Baptiste Telliez, Nir Hacohen, Philip L De Jager, Aviv Regev, Diane Mathis, Christophe Benoist, Immunological Genome Project Consortium

Cell 2016

A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks

A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks

Oren Parnas, Marko Jovanovic, Thomas M Eisenhaure, Rebecca H Herbst, Atray Dixit, Chun Jimmie Ye, Dariusz Przybylski, Randall J Platt, Itay Tirosh, Neville E Sanjana, Ophir Shalem, Rahul Satija, Raktima Raychowdhury, Philipp Mertins, Steven A Carr, Feng Zhang, Nir Hacohen, Aviv Regev

Cell 2015

Intersection of population variation and autoimmunity genetics in human T cell activation

Intersection of population variation and autoimmunity genetics in human T cell activation

Chun Jimmie Ye, Ting Feng, Ho-Keun Kwon, Towfique Raj, Michael T Wilson, Natasha Asinovski, Cristin McCabe, Michelle H Lee, Irene Frohlich, Hyun-il Paik, Noah Zaitlen, Nir Hacohen, Barbara Stranger, Philip De Jager, Diane Mathis, Aviv Regev, Christophe Benoist

Science 2014

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes

Towfique Raj, Katie Rothamel, Sara Mostafavi, Chun Ye, Mark N Lee, Joseph M Replogle, Ting Feng, Michelle Lee, Natasha Asinovski, Irene Frohlich, Selina Imboywa, Alina Von Korff, Yukinori Okada, Nikolaos A Patsopoulos, Scott Davis, Cristin McCabe, Hyun-il Paik, Gyan P Srivastava, Soumya Raychaudhuri, David A Hafler, Daphne Koller, Aviv Regev, Nir Hacohen, Diane Mathis, Christophe Benoist, Barbara E Stranger, Philip L De Jager

Science 2014