Genome Engineering

Discovery of stimulation-responsive immune enhancers with CRISPR activation

Discovery of stimulation-responsive immune enhancers with CRISPR activation

Dimitre R. Simeonov, Benjamin G. Gowen, Mandy Boontanrart, Theodore L. Roth, John D. Gagnon, Maxwell R. Mumbach, Ansuman T. Satpathy, Youjin Lee, Nicolas L. Bray, Alice Y. Chan, Dmytro S. Lituiev, Michelle L. Nguyen, Rachel E. Gate, Meena Subramaniam, Zhongmei Li, Jonathan M. Woo, Therese Mitros, Graham J. Ray, Gemma L. Curie, Nicki Naddaf, Julia S. Chu, Hong Ma, Eric Boyer, Frederic Van Gool, Hailiang Huang, Ruize Liu, Victoria R. Tobin, Kathrin Schumann, Mark J. Daly, Kyle K. Farh, K. Mark Ansel, Chun Jimmie Ye, William J. Greenleaf, Mark S. Anderson, Jeffrey A. Bluestone, Howard Y. Chang, Jacob E. Corn, Alexander Marson

Nature 2017

A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks

A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks

Oren Parnas, Marko Jovanovic, Thomas M Eisenhaure, Rebecca H Herbst, Atray Dixit, Chun Jimmie Ye, Dariusz Przybylski, Randall J Platt, Itay Tirosh, Neville E Sanjana, Ophir Shalem, Rahul Satija, Raktima Raychowdhury, Philipp Mertins, Steven A Carr, Feng Zhang, Nir Hacohen, Aviv Regev

Cell 2015